Lichroma was attached to an Olympus BX51 optical microscope in transmission mode. We used a Human Melanoma slide (7 µm thick) stained with hematoxylin and eosin (H&E) to study the histopathology of malignant melanoma, one of the most dangerous types of skin cancer. Malignant melanoma is caused by the proliferation of cancerous melanocytes, which are cells that produce the pigment melanin. Illuminating the sample with different  colours can easily reveal or hide different structures of the sample without using a fluorescent microscope. The image on the left-hand side was obtained using "Bright Mango" illumination while the image on the right-hand side was obtained using a violet illumination. Of course, many unique colours that Lichroma can generate can reveal or hide features which are of interest or are not relevant. Easy, without using a fluorescent microscope.